CGRP(83-119), rat

CAS No.

CGRP(83-119), rat ( Calcitonin Gene Related Peptide (CGRP) (83-119), rat )

Catalog No. M29902 CAS No.

Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    CGRP(83-119), rat
  • Note
    Research use only, not for human use.
  • Brief Description
    Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
  • Description
    Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.(In Vitro):Calcitonin Gene Related Peptide (CGRP) (83-119), rat belongs to the calcitonin family of neuropeptides which also includes adrenomedullin, amylin, calcitonin, intermedin and calcitonin receptor-stimulating peptide. Calcitonin Gene Related Peptide (CGRP) has two isoforms (αCGRP and βCGRP), and acts through calcitonin receptor-like receptor (CRLR). Calcitonin Gene Related Peptide (CGRP) plays a key role in migraine pathophysiology and is associated with activation of the trigeminovascular system. CGRP prossibly acts postjunctionally in these areas putatively involved in primary headaches.(In Vivo):CGRP is a potent inducer of oedema in rat orofacial tissue. CGRP (100 μL; 8-33 pmol) induces a rapidly developing (5-15?min) and long-lasting (6?h), dose-dependent oedema in the rat cheek. CGRP induces a smaller oedematogenic effect in the rat hind paw also blocked by the CGRP antagonist. CGRP (16 pmol) potentiates the oedema induced by co-injected substance P (3.7 nmol).
  • Synonyms
    Calcitonin Gene Related Peptide (CGRP) (83-119), rat
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    3806.3
  • Molecular Formula
    C162H262N50O52S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

S. Ghatta, et al. Calcitonin gene-related peptide: Understanding its role. Educational Forum. 20.6.2004.
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